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Purchase Sumatriptan Succinate (Imitrex, Imigran) tablets online


How and where to order Imigran, Imitrex (Sumatriptan) 25 mg, 50 mg, 100 mg tablets online:

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Forms: Imitrex, Imigran (Sumatriptan Succinate) 25 mg, 50 mg, 100 mg tablets
Quantity: 5-120 pills
Type: Sumatriptan brand, Imitrex generic, Imigran generic
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Sumatriptan (trade names include Imitrex, Imigran, Cinie, Frimig, Imigran Nasal, Imigran Neo, Imigran Radis, Imigran Subject, Imitrex Nasal, Migraitan, Migraleve Ultra, Migraval, Migrex, Mylan-Sumatriptan, Onzetra Xsail, Oriptan, Sandoz Sumatriptan, Sumacta, Sumatriptan Aurobindo, Sumatriptan Nasal, Suminat, Sumitrex, Teva-Sumatriptan) is an antimigraine medication, cerebral vasoconstrictor from selective serotonin (5HT1) agonists pharmacological group. This medicine is used for the treatment of migraines with or without aura, cluster headaches, post-dural puncture headache. An aura is a strange feeling or visual disturbance that warns you of an attack. Thats why sumatriptan is also called as a "headache medicine". It works by activating vascular 5-HT1 receptors which mediates constriction of the blood vessels.


Imitrex, Imigran (Sumatriptan Succinate)


Related medications:

  • Almotriptan (Almogran)
  • Avitriptan (Avitriptan)
  • Baclofen (Lioresal)
  • Divalproex (Depakote)
  • Donitriptan (Donitriptan)
  • Eletriptan (Relpax)
  • Frovatriptan (Frova)
  • Mebeverine (Colospa)
  • Methocarbamol (Robaxin)
  • Naratriptan (Naramig)
  • Propranolol (Inderal)
  • Pyridostigmine (Mestinon)
  • Rizatriptan (Maxalt)
  • Ropinirole (Requip)
  • Tizanidine (Zanaflex)
  • Topiramate (Topamax)
  • Zolmitriptan (Zomig)


    Pharmacological and medical categories:

  • Analgesics
  • Anti migraine preparations
  • Headache medicines
  • Muscle relaxants
  • Pain relief drugs
  • Selective serotonin agonists
  • Serotonin 5HT1-receptor agonists
  • Triptans


    ATC codes:

  • N - Nervous system
  • N02 - Analgesics
  • N02C - Antimigraine preparations
  • N02CC - Selective serotonin (5HT1) agonists
  • N02CC01 - Sumatriptan


    ICD-10 codes:

  • Migraine - G43
  • Migraine without aura (common migraine) - G43.0
  • Migraine with aura (classical migraine) - G43.1
  • Status migrainosus - G43.2
  • Complicated migraine - G43.3
  • Other migraine - G43.8
  • Migraine, unspecified - G43.9
  • Other headache syndromes - G44


    Indications and usage:

    Imitrex, Imigran (Sumatriptan Succinate) is a serotonin (5-HT1B/1D) receptor agonist (triptan) indicated for acute treatment of migraine with or without aura in adults.


    Dosage and administration:

  • Single dose of Sumatriptan 25 mg, 50 mg, or 100 mg tablet.
  • A second dose should only be considered if some response to the first dose was observed. Separate doses by at least 2 hours.
  • Maximum dose in a 24-hour period: 200 mg.
  • Maximum single dose should not exceed 50 mg in patients with mild to moderate hepatic impairment.


    Overdosage:

    Patients in clinical trials (N = 670) received single oral doses of 140 to 300 mg without significant adverse reactions. Volunteers (N = 174) received single oral doses of 140 to 400 mg without serious adverse reactions.

    Overdose in animals has been fatal and has been heralded by convulsions, tremor, paralysis, inactivity, ptosis, erythema of the extremities, abnormal respiration, cyanosis, ataxia, mydriasis, salivation, and lacrimation.

    The elimination half-life of sumatriptan is approximately 2.5 hours, and therefore monitoring of patients after overdose with Imitrex tablets should continue for at least 12 hours or while symptoms or signs persist.

    It is unknown what effect hemodialysis or peritoneal dialysis has on the serum concentrations of sumatriptan.


    Dosage forms and strengths:

  • Imitrex (Sumatriptan Succinate) tablets 25 mg, 50 mg, 100 mg.
  • Imigran (Sumatriptan Succinate) tablets 50 mg, 100 mg.


    Contraindications:

  • History of coronary artery disease or coronary artery vasospasm.
  • Wolff-Parkinson-White syndrome or other cardiac accessory conduction pathway disorders.
  • History of stroke, transient ischemic attack, or hemiplegic or basilar migraine.
  • Peripheral vascular disease.
  • Ischemic bowel disease.
  • Uncontrolled hypertension.
  • Recent (within 24 hours) use of another 5-HT1 agonist (e.g., another triptan) or of an ergotamine-containing medication.
  • Concurrent or recent (past 2 weeks) use of monoamine oxidase-A inhibitor.
  • Hypersensitivity to Imitrex (angioedema and anaphylaxis seen).
  • Severe hepatic impairment.


    Warnings and precautions:

  • Myocardial ischemia/infarction and Prinzmetal's angina: perform cardiac evaluation in patients with multiple cardiovascular risk factors.
  • Arrhythmias: discontinue Imitrex pills if occurs.
  • Chest/throat/neck/jaw pain, tightness, pressure, or heaviness: generally not associated with myocardial ischemia; evaluate for coronary artery disease in patients at high risk.
  • Cerebral hemorrhage, subarachnoid hemorrhage, and stroke: discontinue Imitrex or Imigran if occurs.
  • Gastrointestinal ischemic reactions and peripheral vasospastic reactions: discontinue Sumatriptan if occurs.
  • Medication overuse headache: detoxification may be necessary.
  • Serotonin syndrome: discontinue this medication if occurs.
  • Seizures: use with caution in patients with epilepsy or a lowered seizure threshold.


    Adverse reactions, side effects:

  • Most common adverse reactions ( >= 2% and > placebo) were paresthesia, warm/cold sensation, chest pain/tightness/pressure and/or heaviness, neck/throat/jaw pain/tightness/pressure, other sensations of pain/pressure/tightness/heaviness, vertigo, and malaise/fatigue.
  • To report suspected adverse reactions of Imitrex and Imigran (Sumatriptan Succinate) tablets contact GlaxoSmithKline or your local FDA.


    Drug interactions:

  • Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because these effects may be additive, use of ergotamine-containing or ergot-type medications (like dihydroergotamine or methysergide) and Imitrex tablets within 24 hours of each other is contraindicated.
  • Monoamine Oxidase-A inhibitors: MAO-A inhibitors increase systemic exposure by 7-fold. Therefore, the use of sumatriptan tablets in patients receiving MAO-A inhibitors is contraindicated.
  • Other 5-HT1 agonists: because their vasospastic effects may be additive, coadministration of Imitrex (Sumatriptan Succinate) tablets and other 5-HT1 agonists (e.g., triptans) within 24 hours of each other is contraindicated.
  • Selective serotonin reuptake inhibitors/serotonin norepinephrine reuptake inhibitors and serotonin syndrome: cases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors.


    Use in specific populations:

    Pregnancy: based on animal data, may cause fetal harm.


    Pregnancy categories:

  • B3 - Australia
  • C - United States (Risk cannot be ruled out)


    Salts and other forms:

  • Sumatriptan Base
  • Sumatriptan Hemisulfate
  • Sumatriptan Succinate


    Synonyms, international and chemical names:

  • 1H-Indole-5-methanesulfonamide, 3-(2-(dimethylamino)ethyl)-N-methyl-
  • 3-(2-(Dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide
  • 3-[2-(Dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide
  • Bursztynian Sumatryptanu
  • Succinato de Sumatriptan
  • Succinato Sumatriptano
  • Sumatriptane
  • Sumatriptani Succinas
  • Sumatriptano
  • Sumatripransuccinat
  • Sumatriptanum
  • Sumatryptan
  • Suproserin


    Brands, generics, trade names:

  • Boots Migraine Relief - Boots
  • Cinie - Zentiva, First Pharma
  • Fermig - Raam de Sahuayo Laboratorios
  • Frimig - Orion Pharma
  • Imigran - GlaxoSmithKline
  • Imigran Nasal - GlaxoSmithKline
  • Imigran Neo - GlaxoSmithKline
  • Imigran Radis - GlaxoSmithKline
  • Imigran Recovery - GlaxoSmithKline
  • Imigran Sprint - GlaxoSmithKline
  • Imigran Subject - GlaxoSmithKline, Kosei Pharma
  • Imigrane - GlaxoSmithKline
  • Imiject - GlaxoSmithKline
  • Imitrex - GlaxoSmithKline
  • Imitrex Instant - GlaxoSmithKline
  • Imitrex Nasal - GlaxoSmithKline
  • Imitrex Statdose - GlaxoSmithKline
  • Imitrex-DF - GlaxoSmithKline
  • Migragesin - Siegfried Laboratorios
  • Migraitan - Bristol Laboratories
  • Migraleve Ultra - Pfizer
  • Migratan - Dabur Pharmaceuticals
  • Migraval - Giempi Laboratorios
  • Migrex - Hexal
  • Mylan-Sumatriptan - Mylan
  • Nograine - Victory Enterprises
  • Nomigren - Liconsa Laboratorios, Goodwill Pharma
  • Onzetra Xsail - Avanir Pharmaceuticals
  • Oriptan - Orion Corporation
  • Sandoz Sumatriptan - Sandoz
  • Sumacta - Actavis
  • Sumamigren - Polpharma, Akrikhin, Dong-A Pharmaceutical, VP Pharma Baru
  • Sumatab - Alphapharm
  • Sumatridex - Dexxon, Dexcel Pharma
  • Sumatriptan - Accord Healthcare, Actavis, Aurobindo, Bluefish Pharmaceuticals, Hexal, Hormosan Pharma, Mepha, Mylan, Sandoz, Teva
  • Sumatriptan Beta - Betapharm Arzneimittel
  • Sumatriptan Dura - Merck, Mylan
  • Sumatriptan Nasal - Sandoz
  • Sumatriptano - Arrow Farmaceutica, Eurofarma
  • Sumatriptan-T - Hexal, Spirig Pharma
  • Sumavel DosePro - Endo Ventures, Patheon, Zogenix
  • Sumigra - Sandoz, Lek
  • Suminat - Sun Pharmaceutical Industries
  • Sumitrex - Sun Pharmaceutical Industries, Bajamed Laboratorios, Synergy Group
  • Teva-Sumatriptan - Teva
  • Triptagic - Tempo Scan Pacific
  • Triptagram - Actavis
  • Xibimer - Dr. Reddy's Laboratories


    APIs used in medicine in combinations with sumatriptan:

  • Naproxen


    Here is a list of popular medications containing sumatriptan as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Imigran
  • Injectable; Injection; Sumatriptan Succinate 6 mg / 0.5 ml
  • Spray; Nasal; Sumatriptan 10 mg / dose
  • Spray; Nasal; Sumatriptan 20 mg / dose
  • Suppositories; Rectal; Sumatriptan Succinate 25 mg
  • Tablets, Film-Coated; Oral; Sumatriptan Succinate 50 mg
  • Tablets, Film-Coated; Oral; Sumatriptan Succinate 100 mg
  • GlaxoSmithKline
  • Aspen
  • B & S Healthcare
  • B.R. Lewis Pharmaceuticals
  • Chemilines
  • Delta Pharma Europe
  • Doncaster Pharmaceuticals Group
  • Euro Registratie
  • Farmagon
  • Firma Chun Cheong
  • Forest Laboratories
  • Lexon UK
  • Medcor Pharmaceuticals
  • O.P.D. Laboratories
  • Primecrown
  • Servipharm
  • Star Pharmaceuticals
  • Zuellig Pharma
  • Imigran Nasal
  • Spray; Nasal; Sumatriptan 10 mg / dose
  • Spray; Nasal; Sumatriptan 20 mg / dose
  • GlaxoSmithKline
  • Aspen
  • Imitrex
  • Injectable; Injection; Sumatriptan Succinate 4 mg / 0.5 ml
  • Injectable; Injection; Sumatriptan Succinate 6 mg / 0.5 ml
  • Injectable; Injection; Sumatriptan Succinate 12 mg / ml
  • Spray; Nasal; Sumatriptan Hemisulfate 5 mg / dose
  • Spray; Nasal; Sumatriptan Hemisulfate 10 mg / dose
  • Spray; Nasal; Sumatriptan Hemisulfate 20 mg / dose
  • Suppositories; Rectal; Sumatriptan Succinate 25 mg
  • Tablets, Film-Coated; Oral; Sumatriptan Succinate 25 mg
  • Tablets, Film-Coated; Oral; Sumatriptan Succinate 50 mg
  • Tablets, Film-Coated; Oral; Sumatriptan Succinate 100 mg
  • GlaxoSmithKline
  • Direct Rx
  • Suminat
  • Injectable; Injection; Sumatriptan Succinate 6 mg / 0.5 ml
  • Spray; Nasal; Sumatriptan 20 mg / dose
  • Spray; Nasal; Sumatriptan 25 mg / dose
  • Tablets; Oral; Sumatriptan Succinate 25 mg
  • Tablets; Oral; Sumatriptan Succinate 50 mg
  • Tablets; Oral; Sumatriptan Succinate 100 mg
  • Sun Pharmaceutical Industries



  • References:

  • Sumatriptan main article on Wikipedia: https://en.wikipedia.org/wiki/Sumatriptan
  • Sumatriptan compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Sumatriptan
  • Sumatriptan Succinate compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Sumatriptan-succinate
  • Sumatriptan medicine on DrugBank: https://go.drugbank.com/drugs/DB00669
  • Sumatriptan Succinate on DrugBank: https://go.drugbank.com/salts/DBSALT001003
  • Triptans on DrugBank: https://go.drugbank.com/categories/DBCAT003231
  • Sumatriptan FAQ on MedlinePlus (revised 11/15/2015): https://medlineplus.gov/druginfo/meds/a601116.html
  • Sumatriptan Nasal FAQ on MedlinePlus (revised 09/15/2019): https://medlineplus.gov/druginfo/meds/a614029.html
  • Sumatriptan Injection FAQ on MedlinePlus (revised 12/15/2017): https://medlineplus.gov/druginfo/meds/a696023.html
  • Serotonin syndrome on MedlinePlus: https://medlineplus.gov/ency/article/007272.htm
  • Aurobindo Sumatriptan Succinate tablets drug label on DailyMed (revised September 19, 2019): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Imitrex (Sumatriptan Succinate) film-coated tablets drug label on DailyMed (revised June 15, 2020): https://dailymed.nlm.nih.gov/dailymed/lookup...
  • Imitrex (Sumatriptan) spray drug label on DailyMed (revised December 14, 2017): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Imitrex (Sumatriptan Succinate) injections drug label on DailyMed (revised December 12, 2011): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Sumatriptan for sale on Pharma Doctor (revised November 2021): https://pharma-doctor.com/sumatriptan.html
  • Sumatriptan containing drugs on Drugs-About.com: https://drugs-about.com/ing/sumatriptan.html
  • Imitrex (Sumatriptan Succinate) 25 mg, 50 mg, 100 mg tablets for oral use official prescribing and patient information from the U.S. FDA (revised 2013): https://www.accessdata.fda.gov/drugsatfda_docs/label...
  • Imitrex (Sumatriptan Succinate) injections for subcutaneous use official prescribing information and instructions for use from the U.S. FDA (revised 11/2015): https://www.accessdata.fda.gov/drugsatfda_docs/label...
  • Imitrex (Sumatriptan Succinate) 25 mg, 50 mg, 100 mg tablets prescribing and patient information from GlaxoSmithKline pharmaceutical company (revised 12/2020): https://gskpro.com/content/dam/global/...
  • Imitrex (Sumatriptan) nasal spray prescribing and patient information, instructions for use from GlaxoSmithKline (revised 12/2017): https://gskpro.com/content/dam/global/...
  • Imigran (Sumatriptan Succinate) 50 mg, 100 mg tablets prescribing information from GlaxoSmithKline (revised 22 April 2015): https://gskpro.com/content/dam/global/...
  • Sumatriptan Succinate tablets 50 mg, 100 mg package information leaflet on Medicines.org.uk (revised December 2020): https://www.medicines.org.uk/emc/files/pil.707.pdf

    Revised: 22 November 2021
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